She took the action after a heated argument with lawyer Donald Kipkorir over the outcome of the elections.
Her father Raila Odinga lost the polls to President William Ruto in what critics said was partly contributed to by poor planning of his campaign secretariat.
Kipkorir had claimed Winnie was part of the Azimio team that sabotaged her father's win.
"Since 2005, I supported freely every political journey of Raila Odinga. Today, Kenya begins a new chapter under President William Ruto. Those that let down Baba like Winnie Odinga and others at Azimio Secretariat now want to troll me. The trolling is misplaced and ill-advised," he said in a tweet.
In response, Winnie told the lawyer to "shut up for once", but later claimed that her account was hacked and later, she deactivated it.
"Twitter hacked. Got it back. Everyone can take it easy now,” she said.
In her Wednesday's tweet, Winnie posted a lineup of the teams that worked with the Azimio candidates during the campaign and election period.